Using voltammetry augmented with physics-based modeling and Bayesian hypothesis testing to identify analytes in electrolyte solutions
نویسندگان
چکیده
Voltammetry is a foundational electrochemical technique that can qualitatively and quantitatively probe electroactive species in solutions as such has been used numerous fields of study. Recently, automation introduced to extend the capabilities voltammetric analysis through approaches Bayesian parameter estimation compound identification. However, opportunities exist enable more versatile methods across wider range solution compositions experimental conditions. Here, we present protocol uses voltammetry, physics-driven models, binary hypothesis testing, inference robust labeling analytes multicomponent multiple techniques. We first describe development this protocol, subsequently validate methodology case study involving five N-functionalized phenothiazine derivatives. In analysis, correctly labels each containing 10H-phenothiazine 10-methylphenothiazine from both cyclic voltammograms square wave voltammograms, demonstrating ability identify redox-active constituents solution. Finally, areas further improvement—such achieving greater detection accuracy—and future applications potentially enhance situ or operando diagnostic workflows.
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ژورنال
عنوان ژورنال: Journal of Electroanalytical Chemistry
سال: 2022
ISSN: ['1873-2569', '1572-6657']
DOI: https://doi.org/10.1016/j.jelechem.2021.115751